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Nucleic Acid Sensors and Type I Interferon Production in Systemic Lupus Erythematosus

The characteristic serologic feature of systemic lupus erythematosus (SLE) is autoantibodies against one’s own nucleic acid or nucleic acid-binding proteins – DNA and RNA-binding nuclear proteins. Circulating autoantibodies can deposit in the tissue, causing inflammation and production of cytokines...

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Detalles Bibliográficos
Autores principales: Shrivastav, Meena, Niewold, Timothy B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791549/
https://www.ncbi.nlm.nih.gov/pubmed/24109483
http://dx.doi.org/10.3389/fimmu.2013.00319