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Nucleic Acid Sensors and Type I Interferon Production in Systemic Lupus Erythematosus
The characteristic serologic feature of systemic lupus erythematosus (SLE) is autoantibodies against one’s own nucleic acid or nucleic acid-binding proteins – DNA and RNA-binding nuclear proteins. Circulating autoantibodies can deposit in the tissue, causing inflammation and production of cytokines...
Autores principales: | Shrivastav, Meena, Niewold, Timothy B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791549/ https://www.ncbi.nlm.nih.gov/pubmed/24109483 http://dx.doi.org/10.3389/fimmu.2013.00319 |
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