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Inhibition of Nitric Oxide Synthase by L-NAME Promotes Cisplatin-Induced Nephrotoxicity in Male Rats

Objective. Nitric oxide (NO) has numerous important functions in the kidney. The role of NO in cisplatin (CP)-induced nephrotoxicity is not completely understood. This study was designed to determine the role of NO synthase inhibitor (L-NAME) on the severity of CP-induced nephrotoxicity in rats. Met...

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Detalles Bibliográficos
Autores principales: Moslemi, Fatemeh, Nematbakhsh, Mehdi, Eshraghi-Jazi, Fatemeh, Talebi, Ardeshir, Nasri, Hamid, Ashrafi, Farzaneh, Moeini, Maryam, Mansouri, Azam, Pezeshki, Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791574/
https://www.ncbi.nlm.nih.gov/pubmed/24167747
http://dx.doi.org/10.1155/2013/242345