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RNA Interference Targeting Snail Inhibits the Transforming Growth Factor β2-Induced Epithelial-Mesenchymal Transition in Human Lens Epithelial Cells

Epithelial-msenchymal transition (EMT) contributes to posterior capsule opacification (PCO) type of cataract. Transcription factors Snail is a key trigger of EMT activated by transforming growth factor β (TGFβ). This study was done to investigate the effect of Snail targeting siRNA on TGFβ2-induced...

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Detalles Bibliográficos
Autores principales: Li, Ping, Jing, Jiaona, Hu, Jianyan, Li, Tiejun, Sun, Yuncheng, Guan, Huaijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791800/
https://www.ncbi.nlm.nih.gov/pubmed/24163761
http://dx.doi.org/10.1155/2013/869101