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Beyond the Limits of Oxygen: Effects of Hypoxia in a Hormone-Independent Prostate Cancer Cell Line

Prostate cancer (PCa) has a high incidence worldwide. One of the major causes of PCa resistance is intratumoral hypoxia. In solid tumors, hypoxia is strongly associated with malignant progression and resistance to therapy, which is an indicator of poor prognosis. The antiproliferative effect and ind...

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Detalles Bibliográficos
Autores principales: Mamede, A. C., Abrantes, A. M., Pedrosa, L., Casalta-Lopes, J. E., Pires, A. S., Teixo, R. J., Gonçalves, A. C., Sarmento-Ribeiro, A. B., Maia, C. J., Botelho, M. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791829/
https://www.ncbi.nlm.nih.gov/pubmed/24167746
http://dx.doi.org/10.1155/2013/918207