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A CRISPR CASe for high-throughput silencing

Manipulation of gene expression on a genome-wide level is one of the most important systematic tools in the post-genome era. Such manipulations have largely been enabled by expression cloning approaches using sequence-verified cDNA libraries, large-scale RNA interference libraries (shRNA or siRNA) a...

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Detalles Bibliográficos
Autores principales: Heintze, Jacob, Luft, Christin, Ketteler, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791873/
https://www.ncbi.nlm.nih.gov/pubmed/24109485
http://dx.doi.org/10.3389/fgene.2013.00193