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Natural Antioxidant-Isoliquiritigenin Ameliorates Contractile Dysfunction of Hypoxic Cardiomyocytes via AMPK Signaling Pathway

Isoliquiritigenin (ISL), a simple chalcone-type flavonoid, is derived from licorice compounds and is mainly present in foods, beverages, and tobacco. Reactive oxygen species (ROS) is a critical factor involved in modulating cardiac stress response signaling during ischemia and reperfusion. We hypoth...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoyu, Zhu, Ping, Zhang, Xiuying, Ma, Yina, Li, Wenguang, Chen, Ji-Mei, Guo, Hui-Ming, Bucala, Richard, Zhuang, Jian, Li, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791876/
https://www.ncbi.nlm.nih.gov/pubmed/24163504
http://dx.doi.org/10.1155/2013/390890