Cargando…

Synthesis and Biological Evaluation of Novel Alkyl-Imidazolyl Carbinols and their Esters: Potent Antimycotics

A novel series of imidazol-5-yl carbinols and their 4-chlorobenzoyl esters has been synthesized by the Grignard reaction and subsequent esterification. These compounds were screened for their antimicrobial activities in an agar diffusion assay. The compounds with C(10) to C(12)-alkyl side chains dis...

Descripción completa

Detalles Bibliográficos
Autores principales: Krauss, Jürgen, Gratzl, Carina, Sturm, Verena, Müller, Christoph, Staudacher, Verena, Schmidt, Christoph Q., Bracher, Franz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791929/
https://www.ncbi.nlm.nih.gov/pubmed/24106663
http://dx.doi.org/10.3797/scipharm.1304-17