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Synthesis and Biological Evaluation of Novel Alkyl-Imidazolyl Carbinols and their Esters: Potent Antimycotics
A novel series of imidazol-5-yl carbinols and their 4-chlorobenzoyl esters has been synthesized by the Grignard reaction and subsequent esterification. These compounds were screened for their antimicrobial activities in an agar diffusion assay. The compounds with C(10) to C(12)-alkyl side chains dis...
Autores principales: | Krauss, Jürgen, Gratzl, Carina, Sturm, Verena, Müller, Christoph, Staudacher, Verena, Schmidt, Christoph Q., Bracher, Franz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Österreichische Apotheker-Verlagsgesellschaft
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791929/ https://www.ncbi.nlm.nih.gov/pubmed/24106663 http://dx.doi.org/10.3797/scipharm.1304-17 |
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