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Validation of a Stability-Indicating Hydrophilic Interaction Liquid Chromatographic Method for the Quantitative Determination of Vitamin K(3) (Menadione Sodium Bisulfite) in Injectable Solution Formulation

A simple, specific, accurate, and stability-indicating method was developed and validated for the quantitative determination of menadione sodium bisulfite in the injectable solution formulation. The method is based on zwitterionic hydrophilic interaction liquid chromatography (ZIC-HILIC) coupled wit...

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Detalles Bibliográficos
Autores principales: Ghanem, Mashhour M., Abu-Lafi, Saleh A., Hallak, Hussein O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791936/
https://www.ncbi.nlm.nih.gov/pubmed/24106670
http://dx.doi.org/10.3797/scipharm.1303-05