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Self-aggregated nanoparticles based on amphiphilic poly(lactic acid)-grafted-chitosan copolymer for ocular delivery of amphotericin B

BACKGROUND: The purpose of this study was to develop a self-aggregated nanoparticulate vehicle using an amphiphilic poly(lactic acid)-grafted-chitosan (PLA-g-CS) copolymer and to evaluate its potential for ocular delivery of amphotericin B. METHODS: A PLA-g-CS copolymer was synthesized via a “protec...

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Detalles Bibliográficos
Autores principales: Zhou, Wenjun, Wang, Yuanyuan, Jian, Jiuying, Song, Shengfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792006/
https://www.ncbi.nlm.nih.gov/pubmed/24106427
http://dx.doi.org/10.2147/IJN.S51186