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Atazanavir–bilirubin interaction: a pharmacokinetic–pharmacodynamic model
PURPOSE: The aim of this work was to analyze the atazanavir–bilirubin relationship, using a new mathematical approach to pharmacokinetic–pharmacodynamic models, for competitive drug interactions based on Michaelis–Menten equations. PATIENTS AND METHODS: Because atazanavir induces an increase of plas...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792011/ https://www.ncbi.nlm.nih.gov/pubmed/24106429 http://dx.doi.org/10.2147/CPAA.S48377 |