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Peptide-Derivatized SB105-A10 Dendrimer Inhibits the Infectivity of R5 and X4 HIV-1 Strains in Primary PBMCs and Cervicovaginal Histocultures

Peptide dendrimers are a class of molecules that exhibit a large array of biological effects including antiviral activity. In this report, we analyzed the antiviral activity of the peptide-derivatized SB105-A10 dendrimer, which is a tetra-branched dendrimer synthetized on a lysine core, in activated...

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Detalles Bibliográficos
Autores principales: Bon, Isabella, Lembo, David, Rusnati, Marco, Clò, Alberto, Morini, Silvia, Miserocchi, Anna, Bugatti, Antonella, Grigolon, Sonia, Musumeci, Giuseppina, Landolfo, Santo, Re, Maria Carla, Gibellini, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792046/
https://www.ncbi.nlm.nih.gov/pubmed/24116111
http://dx.doi.org/10.1371/journal.pone.0076482