PKCα-Specific Phosphorylation of the Troponin Complex in Human Myocardium: A Functional and Proteomics Analysis

AIMS: Protein kinase Cα (PKCα) is one of the predominant PKC isoforms that phosphorylate cardiac troponin. PKCα is implicated in heart failure and serves as a potential therapeutic target, however, the exact consequences for contractile function in human myocardium are unclear. This study aimed to i...

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Detalles Bibliográficos
Autores principales: Kooij, Viola, Zhang, Pingbo, Piersma, Sander R., Sequeira, Vasco, Boontje, Nicky M., Wijnker, Paul J. M., Jiménez, Connie R., Jaquet, Kornelia E., dos Remedios, Cris, Murphy, Anne M., Van Eyk, Jennifer E., van der Velden, Jolanda, Stienen, Ger JM.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792062/
https://www.ncbi.nlm.nih.gov/pubmed/24116014
http://dx.doi.org/10.1371/journal.pone.0074847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792062/
https://www.ncbi.nlm.nih.gov/pubmed/24116014
http://dx.doi.org/10.1371/journal.pone.0074847

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