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Two Functional Variants of IRF5 Influence the Development of Macular Edema in Patients with Non-Anterior Uveitis

OBJECTIVE: Interferon (IFN) signaling plays a crucial role in autoimmunity. Genetic variation in interferon regulatory factor 5 (IRF5), a major regulator of the type I interferon induction, has been associated with risk of developing several autoimmune diseases. In the current study we aimed to eval...

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Detalles Bibliográficos
Autores principales: Márquez, Ana, Cénit, María Carmen, Cordero-Coma, Miguel, Ortego-Centeno, Norberto, Adán, Alfredo, Fonollosa, Alejandro, Díaz Valle, David, Pato, Esperanza, Blanco, Ricardo, Cañal, Joaquín, Díaz-Llopis, Manuel, de Ramón, Enrique, del Rio, María José, García Serrano, José Luis, Artaraz, Joseba, Martín-Villa, José Manuel, Llorenç, Víctor, Gorroño-Echebarría, Marina Begoña, Martín, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792064/
https://www.ncbi.nlm.nih.gov/pubmed/24116155
http://dx.doi.org/10.1371/journal.pone.0076777