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Membrane-To-Nucleus Signaling Links Insulin-Like Growth Factor-1- and Stem Cell Factor-Activated Pathways

Stem cell factor (mouse: Kitl, human: KITLG) and insulin-like growth factor-1 (IGF1), acting via KIT and IGF1 receptor (IGF1R), respectively, are critical for the development and integrity of several tissues. Autocrine/paracrine KITLG-KIT and IGF1-IGF1R signaling are also activated in several cancer...

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Detalles Bibliográficos
Autores principales: Hayashi, Yujiro, Asuzu, David T., Gibbons, Simon J., Aarsvold, Kirsten H., Bardsley, Michael R., Lomberk, Gwen A., Mathison, Angela J., Kendrick, Michael L., Shen, K. Robert, Taguchi, Takahiro, Gupta, Anu, Rubin, Brian P., Fletcher, Jonathan A., Farrugia, Gianrico, Urrutia, Raul A., Ordog, Tamas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792098/
https://www.ncbi.nlm.nih.gov/pubmed/24116170
http://dx.doi.org/10.1371/journal.pone.0076822