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Membrane-To-Nucleus Signaling Links Insulin-Like Growth Factor-1- and Stem Cell Factor-Activated Pathways
Stem cell factor (mouse: Kitl, human: KITLG) and insulin-like growth factor-1 (IGF1), acting via KIT and IGF1 receptor (IGF1R), respectively, are critical for the development and integrity of several tissues. Autocrine/paracrine KITLG-KIT and IGF1-IGF1R signaling are also activated in several cancer...
Autores principales: | Hayashi, Yujiro, Asuzu, David T., Gibbons, Simon J., Aarsvold, Kirsten H., Bardsley, Michael R., Lomberk, Gwen A., Mathison, Angela J., Kendrick, Michael L., Shen, K. Robert, Taguchi, Takahiro, Gupta, Anu, Rubin, Brian P., Fletcher, Jonathan A., Farrugia, Gianrico, Urrutia, Raul A., Ordog, Tamas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792098/ https://www.ncbi.nlm.nih.gov/pubmed/24116170 http://dx.doi.org/10.1371/journal.pone.0076822 |
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