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The Methanol Extract of Azadirachta indica A. Juss Leaf Protects Mice Against Lethal Endotoxemia and Sepsis

In the present study, the inhibitory effect of neem leaf extract (NLE) on lipopolysaccaride (LPS)-induced nitric oxide (NO) and tumor necrosis factor-α (TNF-α) production was examined both in vitro and in vivo. In vitro study revealed that NLE treatment (100 μg/ml) inhibits LPS (100 ng/ml)-induced N...

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Detalles Bibliográficos
Autores principales: Kim, Woong-Hyun, Song, Hyun-Ok, Jin, Chun Mei, Hur, Jong Moon, Lee, Hwa Sung, Jin, Han Yong, Kim, Sung Yeon, Park, Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792208/
https://www.ncbi.nlm.nih.gov/pubmed/24116281
http://dx.doi.org/10.4062/biomolther.2012.20.1.096