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The Structural Basis of Antibody-Antigen Recognition

The function of antibodies (Abs) involves specific binding to antigens (Ags) and activation of other components of the immune system to fight pathogens. The six hypervariable loops within the variable domains of Abs, commonly termed complementarity determining regions (CDRs), are widely assumed to b...

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Detalles Bibliográficos
Autores principales: Sela-Culang, Inbal, Kunik, Vered, Ofran, Yanay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792396/
https://www.ncbi.nlm.nih.gov/pubmed/24115948
http://dx.doi.org/10.3389/fimmu.2013.00302