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Rescuing Infertility of Pick1 Knockout Mice by Generating Testis-specific Transgenic Mice via Testicular Infection

PICK1 (protein interacting with C-kinase 1) is a peripheral membrane protein with high expression in brain, testis, pancreas and other neuroendocrine tissues. Male Pick1 knockout mice are completely infertile, with a phenotype resembling the human disease globozoospermia. Since PICK1 is expressed in...

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Detalles Bibliográficos
Autores principales: Li, Xiumao, Mao, Zhuo, Wu, Min, Xia, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792414/
https://www.ncbi.nlm.nih.gov/pubmed/24100262
http://dx.doi.org/10.1038/srep02842