Cargando…
Rescuing Infertility of Pick1 Knockout Mice by Generating Testis-specific Transgenic Mice via Testicular Infection
PICK1 (protein interacting with C-kinase 1) is a peripheral membrane protein with high expression in brain, testis, pancreas and other neuroendocrine tissues. Male Pick1 knockout mice are completely infertile, with a phenotype resembling the human disease globozoospermia. Since PICK1 is expressed in...
Autores principales: | Li, Xiumao, Mao, Zhuo, Wu, Min, Xia, Jun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792414/ https://www.ncbi.nlm.nih.gov/pubmed/24100262 http://dx.doi.org/10.1038/srep02842 |
Ejemplares similares
-
Overexpression of VEGF in Testis and Epididymis Causes Infertility in Transgenic Mice: Evidence for Nonendothelial Targets for VEGF
por: Korpelainen, Eija I., et al.
Publicado: (1998) -
Rescue of the Friedreich Ataxia Knockout Mutation in Transgenic Mice Containing an FXN-EGFP Genomic Reporter
por: Sarsero, Joseph P., et al.
Publicado: (2014) -
Decreased angiotensin receptor 1 expression in ± AT1 Knockout mice testis results in male infertility and GnRH reduction
por: Zhao, Fangfang, et al.
Publicado: (2021) -
Applications of Transgenic and Knockout Mice in Alcohol Research
por: Bowers, Barbara J.
Publicado: (2000) -
Robust generation of transgenic mice by simple hypotonic solution mediated delivery of transgene in testicular germ cells
por: Usmani, Abul, et al.
Publicado: (2016)