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Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity

Histone acetyltransferases (HATs) assemble into multisubunit complexes in order to target distinct lysine residues on nucleosomal histones. Here, we characterize native HAT complexes assembled by the BRPF family of scaffold proteins. Their plant homeodomain (PHD)–Zn knuckle–PHD domain is essential f...

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Detalles Bibliográficos
Autores principales: Lalonde, Marie-Eve, Avvakumov, Nikita, Glass, Karen C., Joncas, France-Hélène, Saksouk, Nehmé, Holliday, Michael, Paquet, Eric, Yan, Kezhi, Tong, Qiong, Klein, Brianna J., Tan, Song, Yang, Xiang-Jiao, Kutateladze, Tatiana G., Côté, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792477/
https://www.ncbi.nlm.nih.gov/pubmed/24065767
http://dx.doi.org/10.1101/gad.223396.113