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Interleukin-18 and IL-18 Binding Protein

Interleukin-18 (IL-18) is a member of the IL-1 family of cytokines. Similar to IL-1β, IL-18 is synthesized as an inactive precursor requiring processing by caspase-1 into an active cytokine but unlike IL-1β, the IL-18 precursor is constitutively present in nearly all cells in healthy humans and anim...

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Detalles Bibliográficos
Autores principales: Dinarello, Charles A., Novick, Daniela, Kim, Soohyun, Kaplanski, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792554/
https://www.ncbi.nlm.nih.gov/pubmed/24115947
http://dx.doi.org/10.3389/fimmu.2013.00289