Structural basis for the antibody neutralization of Herpes simplex virus

Glycoprotein D (gD) of Herpes simplex virus (HSV) binds to a host cell surface receptor, which is required to trigger membrane fusion for virion entry into the host cell. gD has become a validated anti-HSV target for therapeutic antibody development. The highly inhibitory human monoclonal antibody E...

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Detalles Bibliográficos
Autores principales: Lee, Cheng-Chung, Lin, Li-Ling, Chan, Woan-Eng, Ko, Tzu-Ping, Lai, Jiann-Shiun, Wang, Andrew H.-J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792640/
https://www.ncbi.nlm.nih.gov/pubmed/24100313
http://dx.doi.org/10.1107/S0907444913016776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792640/
https://www.ncbi.nlm.nih.gov/pubmed/24100313
http://dx.doi.org/10.1107/S0907444913016776

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