Rv2969c, essential for optimal growth in Mycobacterium tuberculosis, is a DsbA-like enzyme that interacts with VKOR-derived peptides and has atypical features of DsbA-like disulfide oxidases

The bacterial disulfide machinery is an attractive molecular target for developing new antibacterials because it is required for the production of multiple virulence factors. The archetypal disulfide oxidase proteins in Escherichia coli (Ec) are DsbA and DsbB, which together form a functional unit:...

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Detalles Bibliográficos
Autores principales: Premkumar, Lakshmanane, Heras, Begoña, Duprez, Wilko, Walden, Patricia, Halili, Maria, Kurth, Fabian, Fairlie, David P., Martin, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792642/
https://www.ncbi.nlm.nih.gov/pubmed/24100317
http://dx.doi.org/10.1107/S0907444913017800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792642/
https://www.ncbi.nlm.nih.gov/pubmed/24100317
http://dx.doi.org/10.1107/S0907444913017800

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