Dual-degradable disulfide-containing PEI–Pluronic/DNA polyplexes: transfection efficiency and balancing protection and DNA release

Polymeric gene-delivery vectors to achieve lack of toxicity and a balance between protection and DNA release remains a formidable challenge. Incorporating intracellular environment-responsive degradable bonds is an appreciable step toward developing safer transfection agents. In this study, novel, d...

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Detalles Bibliográficos
Autores principales: Zhang, Lifen, Chen, Zhenzhen, Li, Yanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792845/
https://www.ncbi.nlm.nih.gov/pubmed/24109182
http://dx.doi.org/10.2147/IJN.S49595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792845/
https://www.ncbi.nlm.nih.gov/pubmed/24109182
http://dx.doi.org/10.2147/IJN.S49595

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