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Dynamics of Bcl-xL in Water and Membrane: Molecular Simulations

The Bcl2 family of proteins is capable of switching the apoptotic machinery by directly controlling the release of apoptotic factors from the mitochondrial outer membrane. They have ‘pro’ and ‘anti’-apoptotic subgroups of proteins which antagonize each other’s function; however a detailed atomistic...

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Detalles Bibliográficos
Autores principales: Maity, Atanu, Yadav, Seema, Verma, Chandra S., Ghosh Dastidar, Shubhra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792877/
https://www.ncbi.nlm.nih.gov/pubmed/24116174
http://dx.doi.org/10.1371/journal.pone.0076837