Grb2 Is Regulated by Foxd3 and Has Roles in Preventing Accumulation and Aggregation of Mutant Huntingtin

Growth factor receptor protein binding protein 2 (Grb2) is known to be associated with intracellular growth and proliferation related signaling cascades. Huntingtin (Htt), a ubiquitously expressed protein, when mutated, forms toxic intracellular aggregates - the hallmark of Huntington’s disease (HD)...

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Detalles Bibliográficos
Autores principales: Baksi, Shounak, Jana, Nihar R., Bhattacharyya, Nitai Pada, Mukhopadhyay, Debashis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792889/
https://www.ncbi.nlm.nih.gov/pubmed/24116161
http://dx.doi.org/10.1371/journal.pone.0076792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792889/
https://www.ncbi.nlm.nih.gov/pubmed/24116161
http://dx.doi.org/10.1371/journal.pone.0076792

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