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Personalized treatment strategies in glioblastoma: MGMT promoter methylation status

The identification of molecular genetic biomarkers considerably increased our current understanding of glioma genesis, prognostic evaluation, and treatment planning. In glioblastoma, the most malignant intrinsic brain tumor entity in adults, the promoter methylation status of the gene encoding for t...

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Detalles Bibliográficos
Autores principales: Thon, Niklas, Kreth, Simone, Kreth, Friedrich-Wilhelm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792931/
https://www.ncbi.nlm.nih.gov/pubmed/24109190
http://dx.doi.org/10.2147/OTT.S50208