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An Upstream YY1 Binding Site on the HIV-1 LTR Contributes to Latent Infection

During HIV-1 infection a population of latently infected cells is established. This population is the major obstacle preventing total eradication of the virus from AIDS patients. HIV-1 latency is thought to arise by various mechanisms including repressive chromatin modifications. Transcription facto...

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Detalles Bibliográficos
Autores principales: Bernhard, Wendy, Barreto, Kris, Raithatha, Sheetal, Sadowski, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792934/
https://www.ncbi.nlm.nih.gov/pubmed/24116200
http://dx.doi.org/10.1371/journal.pone.0077052