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Olomoucine II, but Not Purvalanol A, Is Transported by Breast Cancer Resistance Protein (ABCG2) and P-Glycoprotein (ABCB1)

Purine cyclin-dependent kinase inhibitors have been recognized as promising candidates for the treatment of various cancers; nevertheless, data regarding interaction of these substances with drug efflux transporters is still lacking. Recently, we have demonstrated inhibition of breast cancer resista...

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Detalles Bibliográficos
Autores principales: Hofman, Jakub, Kučera, Radim, Cihalova, Daniela, Klimes, Jiri, Ceckova, Martina, Staud, Frantisek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792958/
https://www.ncbi.nlm.nih.gov/pubmed/24116053
http://dx.doi.org/10.1371/journal.pone.0075520