Coval: Improving Alignment Quality and Variant Calling Accuracy for Next-Generation Sequencing Data

Accurate identification of DNA polymorphisms using next-generation sequencing technology is challenging because of a high rate of sequencing error and incorrect mapping of reads to reference genomes. Currently available short read aligners and DNA variant callers suffer from these problems. We devel...

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Detalles Bibliográficos
Autores principales: Kosugi, Shunichi, Natsume, Satoshi, Yoshida, Kentaro, MacLean, Daniel, Cano, Liliana, Kamoun, Sophien, Terauchi, Ryohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792961/
https://www.ncbi.nlm.nih.gov/pubmed/24116042
http://dx.doi.org/10.1371/journal.pone.0075402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792961/
https://www.ncbi.nlm.nih.gov/pubmed/24116042
http://dx.doi.org/10.1371/journal.pone.0075402

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