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A Novel Heavy Domain Antibody Library with Functionally Optimized Complementarity Determining Regions

Today a number of synthetic antibody libraries of different formats have been created and used for the selection of a large number of recombinant antibodies. One of the determining factors for successful isolation of recombinant antibodies from libraries lies in the quality of the libraries i.e. the...

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Detalles Bibliográficos
Autores principales: Mandrup, Ole Aalund, Friis, Niels Anton, Lykkemark, Simon, Just, Jesper, Kristensen, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792991/
https://www.ncbi.nlm.nih.gov/pubmed/24116173
http://dx.doi.org/10.1371/journal.pone.0076834