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Sigma-1 Receptor Enhances Neurite Elongation of Cerebellar Granule Neurons via TrkB Signaling

Sigma-1 receptor (Sig-1R) is an integral membrane protein predominantly expressed in the endoplasmic reticulum. Sig-1R demonstrates a high affinity to various synthetic compounds including well-known psychotherapeutic drugs in the central nervous system (CNS). For that, it is considered as an altern...

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Detalles Bibliográficos
Autores principales: Kimura, Yuriko, Fujita, Yuki, Shibata, Kumi, Mori, Megumi, Yamashita, Toshihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793001/
https://www.ncbi.nlm.nih.gov/pubmed/24116072
http://dx.doi.org/10.1371/journal.pone.0075760