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Nlgn4 knockout induces network hypo-excitability in juvenile mouse somatosensory cortex in vitro

Neuroligins (Nlgns) are postsynaptic cell adhesion molecules that form transynaptic complexes with presynaptic neurexins and regulate synapse maturation and plasticity. We studied the impact of the loss of Nlgn4 on the excitatory and inhibitory circuits in somatosensory cortical slices of juvenile m...

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Detalles Bibliográficos
Autores principales: Delattre, V., La Mendola, D., Meystre, J., Markram, H., Markram, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793213/
https://www.ncbi.nlm.nih.gov/pubmed/24104404
http://dx.doi.org/10.1038/srep02897