Membrane Driven Spatial Organization of GPCRs

Spatial organization of G-protein coupled receptors (GPCRs) into dimers and higher order oligomers has been demonstrated in vitro and in vivo. The pharmacological readout was shown to depend on the specific interfaces, but why particular regions of the GPCR structure are involved, and how ligand-det...

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Detalles Bibliográficos
Autores principales: Mondal, Sayan, Johnston, Jennifer M., Wang, Hao, Khelashvili, George, Filizola, Marta, Weinstein, Harel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793225/
https://www.ncbi.nlm.nih.gov/pubmed/24105260
http://dx.doi.org/10.1038/srep02909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793225/
https://www.ncbi.nlm.nih.gov/pubmed/24105260
http://dx.doi.org/10.1038/srep02909

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