Highly Regioselective Synthesis of Substituted Isoindolinones via Ruthenium-Catalyzed Alkyne Cyclotrimerizations

(Cyclooctadiene)(pentamethylcyclopentadiene)ruthenium chloride [Cp*RuCl(cod)] has been used to catalyze the regioselective cyclization of amide-tethered diynes with monosubstituted alkynes to give polysubstituted isoindolinones. Notably, the presence of a trimethylsilyl group on the diyne generally...

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Detalles Bibliográficos
Autores principales: Foster, Robert W, Tame, Christopher J, Hailes, Helen C, Sheppard, Tom D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793232/
https://www.ncbi.nlm.nih.gov/pubmed/24124414
http://dx.doi.org/10.1002/adsc.201300055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793232/
https://www.ncbi.nlm.nih.gov/pubmed/24124414
http://dx.doi.org/10.1002/adsc.201300055

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