Initial phase I safety of retrovirally transduced human chondrocytes expressing transforming growth factor-beta-1 in degenerative arthritis patients

BACKGROUND AIMS. TissueGene-C (TG-C) represents a cell-mediated gene therapy for localized delivery of allogeneic chondrocytes expressing transforming growth factor (TGF)-β1 directly to the damaged knee joint. Untransduced human chondrocytes (hChonJ cells) have also been incorporated into the TG-C p...

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Detalles Bibliográficos
Autores principales: Ha, Chul-Won, Noh, Moon Jong, Choi, Kyoung Baek, Lee, Kwan Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Informa Healthcare 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793276/
https://www.ncbi.nlm.nih.gov/pubmed/22242865
http://dx.doi.org/10.3109/14653249.2011.629645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793276/
https://www.ncbi.nlm.nih.gov/pubmed/22242865
http://dx.doi.org/10.3109/14653249.2011.629645

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