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Gestational Exposure to a Viral Mimetic Poly(I:C) Results in Long-Lasting Changes in Mitochondrial Function by Leucocytes in the Adult Offspring

Maternal immune activation (MIA) is a potential risk factor for autism spectrum disorder (ASD) and schizophrenia (SZ). In rodents, MIA results in changes in cytokine profiles and abnormal behaviors in the offspring that model these neuropsychiatric conditions. Given the central role that mitochondri...

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Detalles Bibliográficos
Autores principales: Giulivi, Cecilia, Napoli, Eleonora, Schwartzer, Jared, Careaga, Milo, Ashwood, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793312/
https://www.ncbi.nlm.nih.gov/pubmed/24174710
http://dx.doi.org/10.1155/2013/609602