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Gestational Exposure to a Viral Mimetic Poly(I:C) Results in Long-Lasting Changes in Mitochondrial Function by Leucocytes in the Adult Offspring
Maternal immune activation (MIA) is a potential risk factor for autism spectrum disorder (ASD) and schizophrenia (SZ). In rodents, MIA results in changes in cytokine profiles and abnormal behaviors in the offspring that model these neuropsychiatric conditions. Given the central role that mitochondri...
Autores principales: | Giulivi, Cecilia, Napoli, Eleonora, Schwartzer, Jared, Careaga, Milo, Ashwood, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793312/ https://www.ncbi.nlm.nih.gov/pubmed/24174710 http://dx.doi.org/10.1155/2013/609602 |
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