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Constitutive Optimized Production of Streptokinase in Saccharomyces cerevisiae Utilizing Glyceraldehyde 3-Phosphate Dehydrogenase Promoter of Pichia pastoris

A novel expression vector constructed from genes of Pichia pastoris was applied for heterologous gene expression in Saccharomyces cerevisiae. Recombinant streptokinase (SK) was synthesized by cloning the region encoding mature SK under the control of glyceraldehyde 3-phosphate dehydrogenase (GAP) pr...

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Detalles Bibliográficos
Autores principales: Vellanki, Ravi N., Potumarthi, Ravichandra, Doddapaneni, Kiran K., Anubrolu, Naveen, Mangamoori, Lakshmi N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793500/
https://www.ncbi.nlm.nih.gov/pubmed/24171161
http://dx.doi.org/10.1155/2013/268249