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Effect of carvedilol on cardiomyocyte apoptosis in a rat model of myocardial infarction: A role for toll-like receptor 4

OBJECTIVES: Toll-like receptor 4 (TLR4) is crucial in cardiomyocyte apoptosis induced by myocardial infarction (MI) and carvedilol has been reported to have anti-apoptotic effects. We hypothesized that the effects of this agent are in part mediated through TLR4 signaling pathways. MATERIALS AND METH...

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Detalles Bibliográficos
Autores principales: Liu, Qingwei, Zhang, Jianhua, Xu, Yan, Huang, Ying, Wu, Changhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793515/
https://www.ncbi.nlm.nih.gov/pubmed/24130379
http://dx.doi.org/10.4103/0253-7613.117729