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A role for the vesicle-associated tubulin binding protein ARL6 (BBS3) in flagellum extension in Trypanosoma brucei

The small GTPase Arl6 is implicated in the ciliopathic human genetic disorder Bardet–Biedl syndrome, acting at primary cilia in recruitment of the octomeric BBSome complex, which is required for specific trafficking events to and from the cilium in eukaryotes. Here we describe functional characteris...

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Detalles Bibliográficos
Autores principales: Price, Helen P., Hodgkinson, Michael R., Wright, Megan H., Tate, Edward W., Smith, Barbara A., Carrington, Mark, Stark, Meg, Smith, Deborah F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793860/
https://www.ncbi.nlm.nih.gov/pubmed/22609302
http://dx.doi.org/10.1016/j.bbamcr.2012.05.007