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Indole prevents Escherichia coli cell division by modulating membrane potential

Indole is a bacterial signalling molecule that blocks E. coli cell division at concentrations of 3–5 mM. We have shown that indole is a proton ionophore and that this activity is key to the inhibition of division. By reducing the electrochemical potential across the cytoplasmic membrane of E. coli,...

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Detalles Bibliográficos
Autores principales: Chimerel, Catalin, Field, Christopher M., Piñero-Fernandez, Silvia, Keyser, Ulrich F., Summers, David K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793866/
https://www.ncbi.nlm.nih.gov/pubmed/22387460
http://dx.doi.org/10.1016/j.bbamem.2012.02.022