Genetic Background Can Result in a Marked or Minimal Effect of Gene Knockout (GPR55 and CB(2) Receptor) in Experimental Autoimmune Encephalomyelitis Models of Multiple Sclerosis

Endocannabinoids and some phytocannabinoids bind to CB(1) and CB(2) cannabinoid receptors, transient receptor potential vanilloid one (TRPV1) receptor and the orphan G protein receptor fifty-five (GPR55). Studies using C57BL/10 and C57BL/6 (Cnr2 (tm1Zim)) CB(2) cannabinoid receptor knockout mice hav...

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Detalles Bibliográficos
Autores principales: Sisay, Sofia, Pryce, Gareth, Jackson, Samuel J., Tanner, Carolyn, Ross, Ruth A., Michael, Gregory J., Selwood, David L., Giovannoni, Gavin, Baker, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793915/
https://www.ncbi.nlm.nih.gov/pubmed/24130809
http://dx.doi.org/10.1371/journal.pone.0076907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793915/
https://www.ncbi.nlm.nih.gov/pubmed/24130809
http://dx.doi.org/10.1371/journal.pone.0076907

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