Fenofibrate Attenuated Glucose-Induced Mesangial Cells Proliferation and Extracellular Matrix Synthesis via PI3K/AKT and ERK1/2

Excess mesangial extracellular matrix (ECM) and mesangial cell proliferation is the major pathologic feature of diabetic nephropathy (DN). Fenofibrate, a PPARα agonist, has been shown to attenuate extracellular matrix formation in diabetic nephropathy. However, the mechanisms underlying this effect...

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Detalles Bibliográficos
Autores principales: Zeng, Rui, Xiong, Yan, Zhu, Fengming, Ma, Zufu, Liao, Wenhui, He, Yong, He, JinSeng, Li, Wei, Yang, Juan, Lu, Qian, Xu, Gang, Yao, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793917/
https://www.ncbi.nlm.nih.gov/pubmed/24130796
http://dx.doi.org/10.1371/journal.pone.0076836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793917/
https://www.ncbi.nlm.nih.gov/pubmed/24130796
http://dx.doi.org/10.1371/journal.pone.0076836

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