Evaluation of Live Attenuated H7N3 and H7N7 Vaccine Viruses for Their Receptor Binding Preferences, Immunogenicity in Ferrets and Cross Reactivity to the Novel H7N9 Virus

Live attenuated influenza vaccine (LAIV) candidates of the H7 subtype, A/Netherlands/219/03 (H7N7, NL03 ca) and A/chicken/British Columbia/CN-6/2004 (H7N3, BC04 ca), were evaluated for their receptor binding specificity and immunogenicity in ferrets. The BC04 ca virus exhibited α2,3-SA and α2,6-SA d...

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Detalles Bibliográficos
Autores principales: Xu, Qi, Chen, Zhongying, Cheng, Xing, Xu, Lucy, Jin, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793927/
https://www.ncbi.nlm.nih.gov/pubmed/24130801
http://dx.doi.org/10.1371/journal.pone.0076884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793927/
https://www.ncbi.nlm.nih.gov/pubmed/24130801
http://dx.doi.org/10.1371/journal.pone.0076884

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