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Liver-Specific Expressions of HBx and src in the p53 Mutant Trigger Hepatocarcinogenesis in Zebrafish

Hepatocarcinogenesis is a multistep process that starts from fatty liver and transitions to fibrosis and, finally, into cancer. Many etiological factors, including hepatitis B virus X antigen (HBx) and p53 mutations, have been implicated in hepatocarcinogenesis. However, potential synergistic effect...

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Detalles Bibliográficos
Autores principales: Lu, Jeng-Wei, Yang, Wan-Yu, Tsai, Su-Mei, Lin, Yueh-Min, Chang, Pen-Heng, Chen, Jim-Ray, Wang, Horng-Dar, Wu, Jen-Leih, Jin, Shiow-Lian Catherine, Yuh, Chiou-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793937/
https://www.ncbi.nlm.nih.gov/pubmed/24130815
http://dx.doi.org/10.1371/journal.pone.0076951