Cargando…

Liver-Specific Expressions of HBx and src in the p53 Mutant Trigger Hepatocarcinogenesis in Zebrafish

Hepatocarcinogenesis is a multistep process that starts from fatty liver and transitions to fibrosis and, finally, into cancer. Many etiological factors, including hepatitis B virus X antigen (HBx) and p53 mutations, have been implicated in hepatocarcinogenesis. However, potential synergistic effect...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Jeng-Wei, Yang, Wan-Yu, Tsai, Su-Mei, Lin, Yueh-Min, Chang, Pen-Heng, Chen, Jim-Ray, Wang, Horng-Dar, Wu, Jen-Leih, Jin, Shiow-Lian Catherine, Yuh, Chiou-Hwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793937/ https://www.ncbi.nlm.nih.gov/pubmed/24130815 http://dx.doi.org/10.1371/journal.pone.0076951

Ejemplares similares

Omics-based Investigation of Diet-induced Obesity Synergized with HBx, Src, and p53 Mutation Accelerating Hepatocarcinogenesis in Zebrafish Model
por: Yang, Wan-Yu, et al.
Publicado: (2019)

Overexpression of Endothelin 1 Triggers Hepatocarcinogenesis in Zebrafish and Promotes Cell Proliferation and Migration through the AKT Pathway
por: Lu, Jeng-Wei, et al.
Publicado: (2014)

A Novel AURKA Mutant-Induced Early-Onset Severe Hepatocarcinogenesis Greater than Wild-Type via Activating Different Pathways in Zebrafish
por: Su, Zhong-Liang, et al.
Publicado: (2019)

Contribution of C1485T mutation in the HBx gene to human and murine hepatocarcinogenesis
por: Hagiwara, Satoru, et al.
Publicado: (2017)

Complexity of cis-regulatory organization of six3a during forebrain and eye development in zebrafish
por: Chao, Chung-Hao, et al.
Publicado: (2010)

C-terminal truncated HBx initiates hepatocarcinogenesis by downregulating TXNIP and reprogramming glucose metabolism
por: Zhang, Yu, et al.
Publicado: (2020)

Up‐regulation of golgi α‐mannosidase IA and down‐regulation of golgi α‐mannosidase IC activates unfolded protein response during hepatocarcinogenesis
por: Tu, Hsiao‐Chen, et al.
Publicado: (2017)

Correction: C-terminal truncated HBx initiates hepatocarcinogenesis by downregulating TXNIP and reprogramming glucose metabolism
por: Zhang, Yu, et al.
Publicado: (2021)

l-Carnitine ameliorates congenital myopathy in a tropomyosin 3 de novo mutation transgenic zebrafish
por: Hsu, Po-Jui, et al.
Publicado: (2021)

Low molecular weight fucoidan inhibits hepatocarcinogenesis and nonalcoholic fatty liver disease in zebrafish via ASGR/STAT3/HNF4A signaling
por: Wu, Szu‐Yuan, et al.
Publicado: (2017)

Cooperation between liver-specific mutations of pten and tp53 genetically induces hepatocarcinogenesis in zebrafish
por: Luo, Juanjuan, et al.
Publicado: (2021)

EVI1 promotes cell proliferation in HBx-induced hepatocarcinogenesis as a critical transcription factor regulating lncRNAs
por: Huang, Jin-feng, et al.
Publicado: (2016)

Ribose-5-phosphate isomerase A overexpression promotes liver cancer development in transgenic zebrafish via activation of ERK and β-catenin pathways
por: Chou, Yu-Ting, et al.
Publicado: (2019)

Zebrafish WNK Lysine Deficient Protein Kinase 1 (wnk1) Affects Angiogenesis Associated with VEGF Signaling
por: Lai, Ju-Geng, et al.
Publicado: (2014)

The Proapoptotic Gene Bad Regulates Brain Development via p53-Mediated Stress Signals in Zebrafish
por: Hung, Jo-Chi, et al.
Publicado: (2021)

Hepatitis B virus X protein (HBx) enhances centrosomal P4.1-associated protein (CPAP) expression to promote hepatocarcinogenesis
por: Yen, Chia-Jui, et al.
Publicado: (2019)

Identification of a noncanonical function for ribose-5-phosphate isomerase A promotes colorectal cancer formation by stabilizing and activating β-catenin via a novel C-terminal domain
por: Chou, Yu-Ting, et al.
Publicado: (2018)

The Effect of miR-338-3p on HBx Deletion-Mutant (HBx-d382) Mediated Liver-Cell Proliferation through CyclinD1 Regulation
por: Fu, Xiaoyu, et al.
Publicado: (2012)

Src kinases in chondrosarcoma chemoresistance and migration: dasatinib sensitises to doxorubicin in TP53 mutant cells
por: van Oosterwijk, J G, et al.
Publicado: (2013)

Retraction: The Effect of miR-338-3p on HBx Deletion-Mutant (HBx-d382) Mediated Liver-Cell Proliferation through CyclinD1 Regulation
por: Fu, Xiaoyu, et al.
Publicado: (2013)

HBx mutants differentially affect the activation of hypoxia-inducible factor-1α in hepatocellular carcinoma
por: Liu, L-p, et al.
Publicado: (2014)

PIDDosome‐induced p53‐dependent ploidy restriction facilitates hepatocarcinogenesis
por: Sladky, Valentina C, et al.
Publicado: (2020)

Loss of TP53 cooperates with c-MET overexpression to drive hepatocarcinogenesis
por: Zhou, Yi, et al.
Publicado: (2023)

Stimulation of hepatocarcinogenesis by neutrophils upon induction of oncogenic kras expression in transgenic zebrafish
por: Yan, Chuan, et al.
Publicado: (2015)

Proapoptotic Bad Involved in Brain Development, When Severely Defected, Induces Dramatic Malformation in Zebrafish
por: Hung, Jo-Chi, et al.
Publicado: (2021)

Induced Pluripotent Stem Cell Therapy Ameliorates Hyperoxia-Augmented Ventilator-Induced Lung Injury through Suppressing the Src Pathway
por: Liu, Yung-Yang, et al.
Publicado: (2014)

HBx induced AFP receptor expressed to activate PI3K/AKT signal to promote expression of Src in liver cells and hepatoma cells
por: Zhu, Mingyue, et al.
Publicado: (2015)

Nestin Is Essential for Zebrafish Brain and Eye Development through Control of Progenitor Cell Apoptosis
por: Chen, Hua-Ling, et al.
Publicado: (2010)

MiR-145 mediates zebrafish hepatic outgrowth through progranulin A signaling
por: Li, Ya-Wen, et al.
Publicado: (2017)

Heterozygous inactivation of tsc2 enhances tumorigenesis in p53 mutant zebrafish
por: Kim, Seok-Hyung, et al.
Publicado: (2013)

Alcohol and hepatocarcinogenesis
por: Taniai, Makiko
Publicado: (2020)

NEAP/DUSP26 suppresses receptor tyrosine kinases and regulates neuronal development in zebrafish
por: Yang, Chi-Hwa, et al.
Publicado: (2017)

Hepatitis B Virus Oncoprotein HBx Is Not an ATPase
por: Langton, Michelle, et al.
Publicado: (2020)

The Role of HBx Protein in Diseases Beyond the Liver
por: Ai, Liping, et al.
Publicado: (2023)

Intracellular antibody targeting HBx suppresses invasion and metastasis in hepatitis B virus‐related hepatocarcinogenesis via protein phosphatase 2A‐B56γ‐mediated dephosphorylation of protein kinase B
por: Che, Lin, et al.
Publicado: (2022)

WNK1–OSR1 Signaling Regulates Angiogenesis-Mediated Metastasis towards Developing a Combinatorial Anti-Cancer Strategy
por: Hou, Chia-Ying, et al.
Publicado: (2022)

HBx-Induced NF-κB Signaling in Liver Cells Is Potentially Mediated by the Ternary Complex of HBx with p22-FLIP and NEMO
por: Lim, Keo-Heun, et al.
Publicado: (2013)

Interferon-α sensitizes HBx-expressing hepatocarcinoma cells to chemotherapeutic drugs through inhibition of HBx-mediated NF-κB activation
por: Liu, Yanning, et al.
Publicado: (2013)

Absence of p53 Gene Expression in Selenium Molecular Prevention of Chemically Induced Hepatocarcinogenesis in Rats
por: Alwahaibi, Nasar Y., et al.
Publicado: (2011)

GLUTATHIONE S‐TRANSFERASES AND HEPATOCARCINOGENESIS
por: Sato, Kiyomi
Publicado: (1988)

Cannot write session to /tmp/vufind_sessions/sess_skok6tm20g0v0vfirq0rdtboip