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The Novel PPAR α/γ Dual Agonist MHY 966 Modulates UVB–Induced Skin Inflammation by Inhibiting NF-κB Activity

Ultraviolet B (UVB; 290~320nm) irradiation-induced lipid peroxidation induces inflammatory responses that lead to skin wrinkle formation and epidermal thickening. Peroxisome proliferator-activated receptor (PPAR) α/γ dual agonists have the potential to be used as anti-wrinkle agents because they inh...

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Detalles Bibliográficos
Autores principales: Park, Min Hi, Park, Ji Young, Lee, Hye Jin, Kim, Dae Hyun, Chung, Ki Wung, Park, Daeui, Jeong, Hyoung Oh, Kim, Hye Rim, Park, Chan Hum, Kim, So Ra, Chun, Pusoon, Byun, Youngjoo, Moon, Hyung Ryong, Chung, Hae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793945/
https://www.ncbi.nlm.nih.gov/pubmed/24130794
http://dx.doi.org/10.1371/journal.pone.0076820